Treatments for the cold sore There is no cure for herpes virus infections. There are medications and remedies for the cold sore by which you can heal it. Many people can generally feel a cold sore coming on as they are aware of a tingling, burning or itching sensation. They may also have a fever, enlargement of lymph nodes close to the sores, or a general feeling of malaise. in Public bookmarkswith coldsorecoldsoretreatment