- Hahn Lab
Dr. Hahn, located at SCHRI and Children's main campus, is developing a screen for Wilson's disease, which is a genetic mitochondrial disease.
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- Kaeberlein Lab
Research in the Kaeberlein Lab at UW is focused on developing therapies for age-associated diseases by targeting the pathways that regulate aging.
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- Loeb Lab
Dr. Lawrence Loeb, located in the UW Department of Pathology, does work in determining the rate of mutations in mitochondrial DNA in mice. He is trying to study the mechanism of aging.
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- Metabolic Spectroscopy Lab
This lab, at the UW Dept or Radiology, does research on animals to study mitochondrial function in aging and disease. They have many papers on this topic, the most recent of which are titled, "Mitochondrial dysfunction and age" and "Mitochondrial dysfunction: impact on exercise performance and cellular aging." The main researchers seem to be DJ Marcinek and KE Conley, both of whom are professors in the Dept of Radiology.
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- Palmiter Lab
Dr. Palmiter, located in the Biochemistry Department at the UW, seems to focus his research on the nervous system in mice, but he published a paper titled "Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy."
http://www.ncbi.nlm.nih.gov/pubmed/18396137?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
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- Priess Lab
Located at the Hutch, the James Priess' lab uses worms to study the mechanisms that control development from a single-celled embryo into a complex, multi-cellular organism.
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- Roth Lab
At the Hutch, Mark Roth's lab uses worms to study metabolic flexibility and suspended animation, chromosome segregation, and diagnostics.
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- Thomas Lab
At UW, Jim Thomas' lab is using worms to study molecular evolution, especially the evolution and function of gene families implicated in environmental interactions and other rapidly changing selective pressures.
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- Waterston Lab
Bob Waterston is Chair of the Department of Genome Sciences at UW. While a professor at Washington University (in St. Louis, MO) he led the C. elegans genome sequencing project. Now, with an increasing number of complete genome sequences available, his lab's focus has shifted to understanding how sequence information is interpreted to enable life.
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